306. Imaging HSV-1 Viral Oncolysis of Colon Cancer Cells by microPET
نویسندگان
چکیده
منابع مشابه
Positron emission tomography of herpes simplex virus 1 oncolysis.
Viral oncolysis, the destruction of cancer cells by replicating viruses, is under clinical investigation for cancer therapy. Lytic viral replication in cancer cells both destroys the cells and liberates progeny virion to infect adjacent cancer cells. The safety and efficacy of this approach are dependent on selective and robust viral replication in cancer cells rather than in normal cells. Meth...
متن کاملImmunological Aspects of Viral Oncolysis
of disciplines were represented including anthropology, psychology, psychiatry, neurology, mathematics, linguistics, and zoology. One of the major topics was the complexity and variability of primate societies which depend on factors such as the breeding season, estrus cycles, and formation of new groups. Another theme was the evolutionary trend in the naturalistic and biological approaches. An...
متن کاملRapid Delivery of Gold Nanoparticles into Colon Cancer HT-29 Cells by Electroporation: In-vitro Study
Background: Electroporation has become a routine technique for rapid drug delivery for the treatment of cancer. Because of its simplicity and wide range of application, it has been applied for the transfer of gold-nanoparticles and can facilitate entry into target cancer cells. Objective: The aim of this study is finding optimal conditions in order to obtain high GNPs- uptake and cell via...
متن کاملHerpes simplex virus type 1 preferentially targets human colon carcinoma: role of extracellular matrix.
Viral therapy of cancer (viral oncolysis) is dependent on selective destruction of the tumor tissue compared with healthy tissues. Several factors, including receptor expression, extracellular components, and intracellular mechanisms, may influence viral oncolysis. In the present work, we studied the potential oncolytic activity of herpes simplex virus type 1 (HSV-1), using an organ culture sys...
متن کاملAnti-viral evaluation of sesquiterpene coumarins from Ferula assa-foetida against HSV-1
Several complications attributed with Herpes virus related infections and the emergence of drug resistant viruses prompt scientists to search for new drugs. Several terpenoids and coumarins have shown anti HSV effects while no sesquiterpene coumarin have been previously tested for HSV treatment. Three sesquiterpene coumarins [badrakemin acetate (1), kellerin (2) and samarcandin diasteromer (3) ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2006
ISSN: 1525-0016
DOI: 10.1016/j.ymthe.2006.08.361